In a client with Addison's disease, which assessment finding is most likely?

Study for the UWorld Endocrine Test. Dive into flashcards and multiple choice items with explanations and hints. Prepare yourself thoroughly!

In Addison's disease, which is characterized by adrenal insufficiency, the body does not produce enough of the hormones cortisol and aldosterone. One of the hallmark signs of this condition is hyperpigmentation of the skin. This occurs due to increased production of melanocyte-stimulating hormone (MSH) as a result of elevated adrenocorticotropic hormone (ACTH) levels. When cortisol levels are low, the body compensates by producing more ACTH, which in turn stimulates melanocytes to produce more melanin, leading to a darkening of the skin, especially in areas such as the gums and pressure points like the elbows and knees.

This hyperpigmentation can serve as a significant clinical clue in diagnosing and managing Addison's disease, distinguishing it from other conditions that might present with similar symptoms. Other assessment findings typical of Addison's disease include hypotension, fatigue, weight loss, and electrolyte imbalances, particularly hyponatremia and hyperkalemia.

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