In which part of the pituitary gland is ADH (Vasopressin) produced?

Study for the UWorld Endocrine Test. Dive into flashcards and multiple choice items with explanations and hints. Prepare yourself thoroughly!

The correct answer identifies the hypothalamus as the site of production for antidiuretic hormone (ADH), also known as vasopressin. Although ADH is secreted from the posterior pituitary, it is synthesized in the hypothalamus, specifically in the supraoptic and paraventricular nuclei.

Understanding this distinction is crucial because while the posterior pituitary acts as a storage and release site for hormones produced in the hypothalamus, the actual synthesis of ADH occurs in the hypothalamic neurons. This process underscores the relationship between the hypothalamus and the posterior pituitary in the endocrine system. The anterior pituitary, on the other hand, is responsible for producing a different set of hormones, which is why it does not play a role in the production of ADH. The parathyroid gland is involved in calcium metabolism and does not produce any hormones related to water balance, making it unrelated to the question regarding ADH.

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