What condition can occur due to chronic hypersecretion of growth hormone?

Chronic hypersecretion of growth hormone leads to two distinct conditions depending on the timing of the excessive hormone release in relation to the growth plates' closure. In children, before the epiphyseal plates have closed, this hypersecretion results in gigantism, characterized by abnormal growth and increased height due to excessive linear bone growth. This occurs because the growth plates are still open, allowing for continued growth in stature.

In adults, however, once the growth plates have closed, chronic growth hormone excess results in acromegaly. Unlike gigantism, acromegaly is marked by the enlargement of bones and tissues, particularly in the hands, feet, and face. This condition arises because, although growth in height is no longer possible, growth hormone still exerts its effects on peripheral tissues, leading to tissue hypertrophy and metabolic disturbances.

Thus, option B accurately describes the two conditions that can result from chronic hypersecretion of growth hormone, highlighting the importance of developmental timing in the presentation of symptoms associated with this hormonal imbalance.