What hormone's secretion is suppressed by high levels of glucose?

Insulin plays a crucial role in glucose metabolism. When blood glucose levels are high, such as after a meal, the pancreas secretes insulin to help cells absorb glucose and utilize it for energy or store it for future use. However, high levels of glucose also impact the secretion of other hormones in a regulatory manner.

Specifically, high glucose concentrations suppress the secretion of glucagon, which is the hormone produced by the alpha cells of the pancreas that works to increase blood glucose levels. While glucagon secretion is indeed inhibited by high glucose levels, the primary answer here focuses on insulin.

Insulin secretion is a direct response to elevated glucose, and rather than being suppressed, it is stimulated. In contrast, some hormones like cortisol and adrenaline can be involved in glucose metabolism but are not directly suppressed by glucose levels. Understanding the dynamics of insulin and how it is regulated helps clarify how the body maintains glucose homeostasis.