What is a common manifestation of hyperthyroidism that the nurse should expect in a client with Graves' disease?

In clients with hyperthyroidism, particularly those with Graves' disease, a common manifestation is heat intolerance. Graves' disease results from the overproduction of thyroid hormones, which significantly increases metabolic activity. As a consequence, individuals often experience heightened energy expenditure and heat production, leading to a lower tolerance for hot environments and an increased sensitivity to heat. This means they may feel excessively warm or sweaty in situations where others may be comfortable.

This symptom is a hallmark of hyperthyroidism, distinguishing it from other conditions that may cause fatigue or changes in weight. While fatigue can occur due to the body's increased metabolic rate and subsequent depletion of energy reserves, it is not as specific to Graves' disease. Weight gain is generally contrary to expectations in a hyperthyroid state, which typically leads to weight loss due to accelerated metabolism. Cold sensitivity is more commonly associated with hypothyroidism, where decreased thyroid hormone levels result in reduced metabolic activity and an inability to generate adequate body heat. Thus, heat intolerance is the expected and classic manifestation of hyperthyroidism in the context of Graves' disease.