What is Addison's disease characterized by?

Addison's disease is primarily characterized by adrenal insufficiency, which results in lower levels of cortisol and aldosterone. In this condition, the adrenal glands are unable to produce adequate amounts of these hormones due to damage or dysfunction, often caused by autoimmune processes, infections, or other underlying health issues. The deficiency of cortisol leads to symptoms such as fatigue, weight loss, low blood pressure, and skin changes, while low aldosterone levels cause issues with sodium retention and potassium balance, contributing to weakness and electrolyte imbalances.

The correct choice accurately reflects the hallmark of Addison's disease, which is the lack of proper hormone production rather than an overproduction of hormones or features related to other endocrine disorders.