What is primary adrenal insufficiency also known as?

Primary adrenal insufficiency is commonly referred to as Addison's disease, named after the British physician Thomas Addison who first described the condition in the 19th century. This disorder is characterized by the adrenal glands' failure to produce sufficient amounts of key hormones, particularly cortisol and aldosterone. Addison's disease can lead to various symptoms such as fatigue, weakness, weight loss, low blood pressure, and darkening of the skin.

Understanding the context of this condition is crucial because it highlights the importance of adrenal function in maintaining hormonal balance in the body. Cushing's syndrome, Graves' disease, and Hashimoto’s thyroiditis, on the other hand, are distinct disorders affecting different aspects of the endocrine system. Cushing's syndrome is associated with excess cortisol production, Graves' disease involves hyperthyroidism, and Hashimoto’s thyroiditis is an autoimmune condition leading to hypothyroidism. Each of these disorders has different underlying causes, symptoms, and treatment strategies, which further emphasizes why Addison's disease specifically relates to primary adrenal insufficiency.