What is the role of parathyroid hormone in the body?

Study for the UWorld Endocrine Test. Dive into flashcards and multiple choice items with explanations and hints. Prepare yourself thoroughly!

Parathyroid hormone (PTH) plays a crucial role in regulating calcium levels in the body. Its primary function is to increase the concentration of calcium in the blood. This is achieved through several mechanisms: PTH promotes the release of calcium from bones, enhances the reabsorption of calcium in the kidneys, and stimulates the production of active vitamin D (calcitriol) in the kidneys, which in turn increases calcium absorption from the gastrointestinal tract.

By increasing calcium levels in the blood, PTH helps maintain calcium homeostasis, which is essential for various physiological processes, including muscle contraction, blood clotting, and neurotransmission. This regulatory action is vital in preventing hypocalcemia (low calcium levels) that can lead to muscle spasms and other health issues.

The other options, focusing on lowering calcium levels, regulating blood sugar, or promoting thyroid hormone synthesis, do not accurately represent the primary function of parathyroid hormone, as those roles are regulated by other hormones and mechanisms in the body.

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