What skin finding should be reported as it may indicate insulin resistance?

Study for the UWorld Endocrine Test. Dive into flashcards and multiple choice items with explanations and hints. Prepare yourself thoroughly!

The skin finding that may indicate insulin resistance is brownish skin thickening on the neck. This condition is known as acanthosis nigricans, which is characterized by the appearance of velvety, dark patches of skin, often seen in body folds such as the neck, armpits, and groin.

Acanthosis nigricans is particularly associated with insulin resistance and metabolic syndrome, as high insulin levels can lead to increased growth of skin cells and the subsequent thickening and darkening of the skin. Identifying this sign is crucial, especially in clinical settings where assessing for conditions linked to insulin resistance, like type 2 diabetes or obesity, is important.

In contrast, the other choices do not directly correlate with significant indicators of insulin resistance. A body mass index of 23 kg/m² is considered within the normal range, and while it may not rule out insulin resistance entirely, it does not indicate it by itself. A fasting total cholesterol of 180 mg/dL is also a typical value and does not suggest insulin resistance. Lastly, a round pale pink mole does not have a relationship with insulin resistance and is generally associated with benign skin lesions. Recognizing acanthosis nigricans is therefore essential for the

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