Which medication is primarily used to manage hypertension in the provided case?

Study for the UWorld Endocrine Test. Dive into flashcards and multiple choice items with explanations and hints. Prepare yourself thoroughly!

Hydrochlorothiazide is primarily used to manage hypertension due to its effectiveness as a thiazide diuretic. Thiazide diuretics work by promoting the excretion of sodium and water from the kidneys, thereby reducing blood volume and lowering blood pressure. This class of medications is often considered a first-line treatment for hypertension and is particularly useful in patients with mild to moderate high blood pressure.

In addition to directly reducing blood pressure, hydrochlorothiazide can have other beneficial effects such as positive impacts on the metabolic profile of some patients and potential advantages in treating conditions like heart failure or edema. When evaluating hypertension management, it’s important to recognize that hydrochlorothiazide is chosen for its efficacy, safety profile, and the vast evidence supporting its use in various patient populations.

The other medications listed serve different primary purposes that do not align with the direct management of hypertension. For instance, insulin lispro is primarily an ultra-rapid-acting insulin used in diabetes management, while spironolactone is a potassium-sparing diuretic often used for conditions such as heart failure and certain cases of resistant hypertension, not first-line management. Detemir is a long-acting insulin, also focused on glucose management in diabetes, and

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